J R Army Med Corps 160:109-116 doi:10.1136/jramc-2014-000254
  • Review

Combat Casualty Care research programme

  1. S Watts
  1. Biomedical Sciences Department, Dstl Porton Down, Salisbury, UK
  1. Correspondence to Dr E Kirkman, Biomedical Sciences Department, Dstl Porton Down, Salisbury SP4 0JQ, UK; ekirkman{at}


The Combat Casualty Care research programme is an integrated suite of projects designed to address Defence Medical Services’ research needs for casualty care. The programme covers a broad spectrum of topics ranging from the pathophysiological and immunological impact of military relevant injuries to the effects of these disturbances on the response to early treatment. Dstl Porton Down has a long history of studying military injuries and has developed models, both in vivo and physical, to address the research needs. The work is conducted in close collaboration with clinical colleagues at the Royal Centre for Defence Medicine who have direct experience of the clinical issues faced by combat casualties and insights into the potential clinical implications of emerging strategies. This article reviews progress in research areas spanning forward resuscitation, with a particular focus on blast-related injuries, trauma coagulopathy, effects of drugs on the response to haemorrhage and deployed research. A significant ‘value added’ component has been the underpinning of higher degrees for seconded military clinicians at Dstl Porton Down who have made a valuable contribution to the overall programme.

  • Received January 21, 2014.
  • Accepted January 21, 2014.
  • Published Online First 26 February 2014

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