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Cardiovascular Physiology at High Altitude
  1. T Hooper, Registrar in Anaesthesia1 and
  2. Surg Cdr Adrian Mellor, FRCA RN, Consultant Anaesthetist2
  1. 1Sir Humphry Davy Department of Anaesthesia, University Hospitals Bristol NHS Foundation Trust, Marlborough Street, Bristol BS2 8HW
  2. 2James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW 01642 850850 dramellor{at}


The role of the cardiovascular system is to deliver oxygenated blood to the tissues and remove metabolic effluent. It is clear that this complex system will have to adapt to maintain oxygen deliver in the profound hypoxia of high altitude. The literature on the adaptation of both the systemic and pulmonary circulations to high altitude is reviewed.

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